EFFECT OF ETHANOL EXTRACT PAPAYA LEAF (CARICA PAPAYA L) CONCENTRATION AGAINST LARVAE AEDES AEGYPTI DEATH

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Abstract

By : I Gusti Ayu Prapti Adnyani

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Faculties : Fakultas Kedokteran

Department : PS. PENDIDIKAN DOKTER

Until now dengue vaccines and drugs do not exist, so the main control that can be done is to break the chain of transmission by vector control. Vector control with synthetic materials can cause environmental hazards such resistance arises in the vector population. This study aims to determine the effectiveness of the ethanol extract of leaves of papaya (Carica papaya L) as the Aedes aegypti mosquito larvicides. The design of this study is purely experimental with randomizesd post test only control group design. The sample used is Aedes aegypti larvae as much as 150 animals. The independent variable in this study is the concentration of the ethanol extract of papaya leaf, the dependent variable is the death of Aedes aegypti larvae. Data were analyzed by One Way Anova followed by Post Hoc test. At a concentration of 1% after observation for 24 hours, the average number of Aedes aegypti larvae mortality is 100%. One Way Anova obtain results p value = 0.000 (p <0.05), which means that there is a statistically significant difference in mortality between groups Aedes aegypti larvae were studied. Post hoc analysis results to obtain the results are significant differences in mortality between the concentrations of 0% and 0.125%, 0% and 0.25%, 0% and 0.5%, 0% and 1%, and 0.0625% and 1%, but there is no significant difference in mortality between the concentration of 0.0625 compared with controls. All concentrations of ethanol extract of papaya (Carica papaya L) can cause the death of larvae of Aedes aegypti, with the highest number of deaths at a concentration of 1%. Further research is needed with larger sample sizes and more varied concentrations.

Keyword : papaya leaves, larvae, dengue hemorhagic fever

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