CORELATION OF GRADING AND LYMPHOVASCULAR INVASION WITH AXILLARY LYMPH NODE METASTASE IN BREAST CANCER

SKRIPSI

Abstract

By : Albert Simon

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Faculties : Fakultas Kedokteran

Department : PS. PENDIDIKAN DOKTER

In Indonesia, breast cancer is cancer with the 2nd highest incidence rate. This study was conducted to know the correlation between breast cancer grading and lymphovascular invasion (LVI) with axillary lymph node metastases. This study was carried out by ; 1) obtaining the sample from medical record and pathology anatomy examination report of breast cancer patient from RSUP Sanglah 2013, 2) examining the correlation between grading with axillary lymph node metastases and correlation between LVI with axillary lymph node metastases using chisquare, 3) Examining the strength of correlation between grading with axillary lymph node metastases and LVI with axillary lymph node metastases using RO. This study consist of 51 samples which diagnosed with advance breast cancer. The result of this study shows ; 1) no correlation between grading with axillary lymph node metastases, 2) there is correlation between LVI with axillary lymph node metastases, 3) the strength of correlation between LVI with axillary lymph node metastases are RO=5.34 with the percentage of 84%. In conclusion, LVI is correlated with axillary lymph node metastases. Further study about other factors which effecting the axillary lymph node metastases and the correlation of grading and LVI with axillary lymph node metastases in early breast cancer should be conducted in order to give more clear information.

Keyword : Breast cancer, grading, lymphovascular invasion, metastases

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