PREVALENCE OF Enterobacter gergoviae EXTENDED SPECTRUM BETA LAKTAMASE (ESBL) FROM BLOOD SPECIMENT AT MICROBIOLOGY CLINIC INSTALATION RSUP SANGLAH FROM NOVEMBER 2012- NOVEMBER 2013

SKRIPSI

Abstract

By : Kadek Mien Dwi Cahyani

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Faculties : Fakultas Kedokteran

Department : PS. PENDIDIKAN DOKTER

Infection is the leading cause of death all over the world. Infection by Extended Spectrum Beta Lactamase (ESBL) bacteria easily resistant to antibiotics. Enterobacter gergoviae ESBL caused a high morbidity and mortality rate. This study conducted to know the prevalence of E.gergoviae ESBL, sensitivity pattern to antibiotics, and specific distribution based on care units. This study used descriptive design. Of 100 samples ESBL positives, 29% are E.gergoviae isolates, and of total 62 samples, 29 E.gergoviae are ESBL positives (47%). Sensitive antibiotics for E.gergoviae ESBL including amikacin, lefoperazone sulbactam, piperacillin / tazobactam, ertapenem, meropenem, levofloxacin, and imipenem. Meanwhile, ampicillin, chloramphenicol, gentamycin, tetracycline, trimethoprim sulfamethoxazole, cefotaxime, cefuroxime, cephalotin, and aztreonam are insensitive. Specific distribution based on care units mostly on intensive care unit (ICU) which is 27%. Ampicillin and cephalotin has the lowest sensitivity amongst antibiotics (4% each) and imipenem is the most sensitive (93%) against E.gergoviae ESBL.

Keyword : Enterobacter gergoviae, Extended Spectrum Beta Lactamase (ESBL), antibiotic, intencive care unit (ICU)

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